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Labial melanotic macule Oral melanotic macula on the lower labial vestibular mucosa on a Download Scientific Diagram Melanocytic Naevus Ballarat Skin Cancer Centre Despite the name "melanosis," the pigment isn't melanin. The Pigment: It is actually lipofuscin, a "wear and tear" pigment. The Process: Anthraquinone laxatives cause apoptosis (cell death) of the colonic epithelial cells.
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