Depression treatment with natural acetyl l carnitine? Could a mitochondrial metabolite known as acetyl L carnitine (LAC) yield a new biomarker for depression and potential new therapies? Dr. Carla Nasca, an @nyugrossman assistant professor of psychiatry and of neuroscience and physiology, Acetyl L Carnitine, 100 Vegetarian Capsules Acetyl L carnitine protects against LPS induced depression via PPAR induced inhibition of NF B NLRP3 pathway