Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update Oral Melanotic Macule: Symptoms and Treatment Skinsight Oral pigmented lesions: a pragmatic approach to diagnosis and management Faculty Dental Journal Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule.